IMPORTANT SAFETY INFORMATION

METROGEL^® (metronidazole) Gel, 1% is indicated for the topical treatment of inflammatory lesions of rosacea. The most common adverse reactions that have been reported with the topical use of METROGEL^® 1% are sore throat/nasal congestion, upper respiratory tract infections, and headaches, as well as dryness, scaling, itching, and stinging. Transient redness, metallic taste, tingling or numbness of extremities and nausea have also been reported with the topical use of metronidazole. Tell your doctor if you are using blood thinning drugs like coumarin or warfarin, because there is a risk of interaction with metronidazole. Do not use METROGEL^® 1% if you are allergic to metronidazole or any of the other ingredients in the gel. METROGEL^® 1% is available by prescription only. Talk to your doctor to learn more about METROGEL^® 1%.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.